Evaluation of Clonorchis sinensis Recombinant 7-Kilodalton Antigen for Serodiagnosis of Clonorchiasis-Reference-Cited by-同舟云学术

Evaluation of Clonorchis sinensis Recombinant 7-Kilodalton Antigen for Serodiagnosis of Clonorchiasis

Published:2004-07 Issue:4 Volume:11 Page:814-817
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Zhao Qin-Ping¹²³⁴,Moon Sung-Ung¹²³⁴,Lee Hyeong-Woo¹²³⁴,Na Byoung-Kuk¹²³⁴,Cho Seung-Yull¹²³⁴,Kong Yoon¹²³⁴,Jiang Ming-Sen¹²³⁴,Li Ai-Hua¹²³⁴,Kim Tong-Soo¹²³⁴

Affiliation:

1. Department of Tropical and Endemic Parasitic Diseases, National Institute of Health, Seoul 122-701

2. Department of Molecular Parasitology and Center for Molecular Medicine, Sungkyunkwan University School of Medicine and Samsung Biomedical Research Institute, Suwon 440-746, Korea

3. Department of Parasitology, School of Medicine, Wuhan University, Wuhan 430071

4. State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China

Abstract

ABSTRACT The diagnostic applicability of the Clonorchis sinensis recombinant 7-kDa protein was evaluated. In enzyme-linked immunosorbent assays and immunoblots, the protein showed high sensitivities (81.3 and 71.9%, respectively) and specificities (92.6 and 89.7%, respectively) for sera obtained from various helminthic infections. Some paragonimiasis sera showed cross-reactions. The antigen might be valuable in the serodiagnosis of human clonorchiasis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.11.4.814-817.2004

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