Thymidine-Dependent Small-Colony Variants of Staphylococcus aureus Exhibit Gross Morphological and Ultrastructural Changes Consistent with Impaired Cell Separation-Reference-Cited by-同舟云学术

Thymidine-Dependent Small-Colony Variants of Staphylococcus aureus Exhibit Gross Morphological and Ultrastructural Changes Consistent with Impaired Cell Separation

Published:2003-01 Issue:1 Volume:41 Page:410-413
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Kahl Barbara C.¹,Belling Gunnar¹,Reichelt Rudolf²,Herrmann Mathias³,Proctor Richard A.⁴,Peters Georg¹

Affiliation:

1. Institute of Medical Microbiology

2. Institute for Medical Physics and Biophysics, University of Muenster Hospital and Clinics, Muenster

3. Institute of Microbiology and Hygiene, University of Saarland, Homburg, Germany

4. Department of Medicine and Medical Microbiology/Immunology, University of Wisconsin Medical School, Madison, Wisconsin

Abstract

ABSTRACT Thymidine-dependent small-colony variants (SCV) of Staphylococcus aureus exhibited unusual colony morphology with “fried-egg” or pinpoint white colonies on agar plates and pleomorphic cocci as determined by Gram staining. Electron microscopy revealed enlarged cocci with incomplete or multiple cross walls consistent with impaired cell separation. Fried-egg SCV phenotypes could be reversed by thymidine supplementation.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.41.1.410-413.2003

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