Identification of Chicken CD44 as a Novel B Lymphocyte Receptor for Infectious Bursal Disease Virus

Author:

Liu Aijing1,Pan Qing1,Wang Suyan1,Zhang Yu1,Li Yue1,Wang Yongqiang1,Qi Xiaole1,Gao Li1,Liu Changjun1,Zhang Yanping1,Cui Hongyu1,Li Kai1,Wang Xiaomei12ORCID,Gao Yulong1ORCID

Affiliation:

1. Division of Avian Immunosuppressive Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

2. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou University, Yangzhou, China

Abstract

Infectious bursal disease virus (IBDV) causes severe immunosuppressive disease in chickens, inducing huge economic losses for the poultry industry. However, the specific mechanism of IBDV invading host cells of IBDV was not very clear.

Funder

Heilongjiang Provincial Natural Science Foundation of China

Agriculture Research System of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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