In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis That Are Susceptible or Resistant to First-Line Antituberculous Drugs-Reference-Cited by-同舟云学术

In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis That Are Susceptible or Resistant to First-Line Antituberculous Drugs

Published:2003-01 Issue:1 Volume:47 Page:416-417
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Alcalá Luis¹,Ruiz-Serrano María Jesús¹,Pérez-Fernández Turégano Cristina¹,García de Viedma Darío¹,Díaz-Infantes Marisol¹,Marín-Arriaza Mercedes¹,Bouza Emilio¹

Affiliation:

1. Servicio de Microbiología y Enfermedades Infecciosas, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain

Abstract

ABSTRACT We evaluated 117 isolates of Mycobacterium tuberculosis for susceptibility to linezolid by the proportion and E-test methods. Linezolid showed high in vitro activity, with all the strains inhibited by ≤1 μg of the drug per ml. E-test MICs were at least 4 dilutions lower than their equivalents by the standard proportion method.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.1.416-417.2003

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