Use of high-dose fluconazole as salvage therapy for cryptococcal meningitis in patients with AIDS-Reference-Cited by-同舟云学术

Use of high-dose fluconazole as salvage therapy for cryptococcal meningitis in patients with AIDS

Published:1992-03 Issue:3 Volume:36 Page:690-692
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Berry A J¹,Rinaldi M G¹,Graybill J R¹

Affiliation:

1. Audie L. Murphy Memorial Veterans Hospital, San Antonio, Texas.

Abstract

Eight patients with AIDS were treated orally with 800 mg of fluconazole daily for cryptococcal meningitis for a mean duration of 4.5 months. Previous antifungal treatment had failed for all of the patients. No major toxicity was observed. Three patients died from cryptococcal infection. High-dose fluconazole may be effective salvage therapy for cryptococcal meningitis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.36.3.690

Reference13 articles.

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4. Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome;Chuck S. L.;N. Engl. J. Med.,1989

5. Cryptococcal meningitis in patients with AIDS;Dismukes W. E.;J. Infect. Dis.,1988

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