A Mycobacterial Systems Resource for the Research Community-Reference-Cited by-同舟云学术

A Mycobacterial Systems Resource for the Research Community

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Judd J. A.¹,Canestrari J.¹,Clark R.¹,Joseph A.¹,Lapierre P.¹^ORCID,Lasek-Nesselquist E.¹,Mir M.¹,Palumbo M.¹,Smith C.¹,Stone M.¹,Upadhyay A.¹,Wirth S. E.¹,Dedrick R. M.²,Meier C. G.²,Russell D. A.²^ORCID,Dills A.³,Dove E.³,Kester J.³,Wolf I. D.³,Zhu J.³,Rubin E. R.³,Fortune S.³,Hatfull G. F.²^ORCID,Gray T. A.¹⁴,Wade J. T.¹⁴^ORCID,Derbyshire K. M.¹⁴^ORCID

Affiliation:

1. Wadsworth Center, New York State Department of Health, Albany, New York, USA

2. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

3. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA

4. Department of Biomedical Sciences, University at Albany, Albany, New York, USA

Abstract

Diseases caused by mycobacterial species result in millions of deaths per year globally, and present a substantial health and economic burden, especially in immunocompromised patients. Difficulties inherent in working with mycobacterial pathogens have hampered the development and application of high-throughput genetics that can inform genome annotations and subsequent functional assays.

Funder

HHS | National Institutes of Health

Howard Hughes Medical Institute

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02401-20

Reference59 articles.

1. Next-Generation High-Throughput Functional Annotation of Microbial Genomes

2. Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection