A Novel Toxoplasma Inner Membrane Complex Suture-Associated Protein Regulates Suture Protein Targeting and Colocalizes with Membrane Trafficking Machinery-Reference-Cited by-同舟云学术

A Novel Toxoplasma Inner Membrane Complex Suture-Associated Protein Regulates Suture Protein Targeting and Colocalizes with Membrane Trafficking Machinery

Published:2021-10-26 Issue:5 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Chern Jessica H.¹,Pasquarelli Rebecca R.²,Moon Andy S.¹,Chen Allan L.¹,Sha Jihui³,Wohlschlegel James A.³,Bradley Peter J.¹²^ORCID

Affiliation:

1. Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA

2. Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA

3. Department of Biological Chemistry and Institute of Genomics and Proteomics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA

Abstract

The inner membrane complex (IMC) is a peripheral membrane and cytoskeletal system that is organized into intriguing rectangular plates at the periphery of the parasite. The IMC plates are delimited by an array of IMC suture proteins that are tethered to both the membrane and the cytoskeleton and are thought to provide structure to the organelle.

Funder

HHS | National Institutes of Health

UC | University of California, Los Angeles

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02455-21

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