First Description of KPC-2-Producing Klebsiella oxytoca in Brazil

Abstract

ABSTRACTThe present work reports the detection of the first case of nosocomialKlebsiella oxytocaproducing class A carbapenemase KPC-2 in Brazil. The isolate KPN106 carried a 65-kb IncW-type plasmid that harbors theblaKPCgene and Tn4401b. Moreover, we detected the presence of a class 1 integron containing a new allele,arr-8, followed by a 5′-truncateddhfrIIIcgene. In view of the recent results, we emphasize the high variability of the bacterial and genetic hosts of this resistance determinant.