Complete Sequence of the IncA/C 1 Plasmid pCf587 Carrying bla PER-2 from Citrobacter freundii-Reference-Cited by-同舟云学术

Complete Sequence of the IncA/C 1 Plasmid pCf587 Carrying bla PER-2 from Citrobacter freundii

Published:2018-05 Issue:5 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ruggiero Melina¹²,Girlich Delphine³⁴,Dabos Laura³⁴,Power Pablo¹²^ORCID,Naas Thierry³⁴⁵,Gutkind Gabriel¹²

Affiliation:

1. Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Microbiología, Inmunología y Biotecnología, Cátedra de Microbiología, Buenos Aires, Argentina

2. Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

3. EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx LERMIT, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France

4. Evolution and Ecology of Resistance to Antibiotics Unit, Institut Pasteur-APHP-Université Paris Sud, Paris, France

5. Associated French National Reference Center for Antibiotic Resistance, Carbapenemase-Producing Enterobacteriaceae, Le Kremlin-Bicêtre, France

Abstract

ABSTRACT The bla PER-2 -harboring plasmid pCf587 (191,541 bp) belongs to lineage IncA/C 1 and is closely related to pRA1. It contains a large resistance island including the bla PER-2 gene between two copies of IS Kox2 -like elements, the toxin-antitoxin module pemK-pemI , several other resistance genes inserted within a Tn 2 transposon, a Tn 21 -like structure, and a class 1 integron. pCf587 belongs to sequence type 13 (ST13), a new plasmid multilocus sequence typing (pMLST) ST.

Funder

Université Paris Sud

French National Research Agency

MINCyT | Agencia Nacional de Promoción Científica y Tecnológica

Universidad de Buenos Aires

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00006-18

Reference32 articles.