Optimal Expression of the Envelope Glycoprotein of Orthobornaviruses Determines the Production of Mature Virus Particles-Reference-Cited by-同舟云学术

Optimal Expression of the Envelope Glycoprotein of Orthobornaviruses Determines the Production of Mature Virus Particles

Published:2021-02-10 Issue:5 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Sakai Madoka¹²,Fujita Yoko³⁴,Komorizono Ryo¹,Kanda Takehiro¹⁵,Komatsu Yumiko¹⁶,Noda Takeshi³⁴,Tomonaga Keizo¹²⁵^ORCID,Makino Akiko¹²^ORCID

Affiliation:

1. Laboratory of RNA Viruses, Department of Virus Research, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

2. Laboratory of RNA Viruses, Department of Mammalian Regulatory Network, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

3. Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

4. Laboratory of Ultrastructural Virology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

5. Department of Molecular Virology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

6. K-CONNEX, Kyoto, Japan

Abstract

Most viruses causing persistent infection produce few infectious particles from the infected cells. Borna disease virus 1, a member of the genus Orthobornavirus , is an RNA virus that persistently infects the nucleus and has been applied to vectors for long-term gene expression.

Funder

Japan Agency for Medical Research and Development

Ministry of Education, Culture, Sports, Science and Technology

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02221-20

Reference71 articles.

1. RNA Viruses as Tools in Gene Therapy and Vaccine Development