Metabolic Differentiation of Co-occurring Accumulibacter Clades Revealed through Genome-Resolved Metatranscriptomics

Author:

McDaniel Elizabeth A.12ORCID,Moya-Flores Francisco345,Keene Beach Natalie36,Camejo Pamela Y.37,Oyserman Ben O.89,Kizaric Matthew3,Khor Eng Hoe3,Noguera Daniel R.310ORCID,McMahon Katherine D.13

Affiliation:

1. Department of Bacteriology, University of Wisconsin—Madison, Madison, Wisconsin, USA

2. Microbiology Doctoral Training Program, University of Wisconsin—Madison, Madison, Wisconsin, USA

3. Department of Civil and Environmental Engineering, University of Wisconsin—Madison, Madison, Wisconsin, USA

4. Geroscience Center for Brain Health and Metabolism (GERO), Santiago, Chile

5. Millenium Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Iniciativa Científica Milenio, Santiago, Chile

6. Carollo Engineers, Inc., Broomfield, Colorado, USA

7. Millennium Institute for Integrative Biology (iBio), Santiago, Chile

8. Bioinformatics Group, Wageningen University and Research, Wageningen, The Netherlands

9. Microbial Ecology, Netherlands Institute of Ecological Research, Wageningen, The Netherlands

10. DOE Great Lakes Bioenergy Research Center, Madison, Wisconsin, USA

Abstract

Candidatus Accumulibacter phosphatis” is a model polyphosphate-accumulating organism that has been studied using genome-resolved metagenomics, metatranscriptomics, and metaproteomics to understand the EBPR process. Within the Accumulibacter lineage, several similar but diverging clades are defined by the shared sequence identity of the polyphosphate kinase ( ppk1 ) locus.

Funder

MINEDUC | Comisión Nacional de Investigación Científica y Tecnológica

National Science Foundation

University of Wisconsin-Madison

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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