Individuality of the Extremely Premature Infant Gut Microbiota Is Driven by Ecological Drift

Author:

Seki David12,Schauberger Clemens3,Hausmann Bela45ORCID,Berger Angelika2,Wisgrill Lukas2,Berry David14

Affiliation:

1. Centre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, Division of Microbial Ecology, University of Vienna, Vienna, Austria

2. Department of Pediatrics and Adolescent Medicine, Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria

3. Hadal & Nordcee, Department of Biology, University of Southern Denmark, Odense, Denmark

4. Joint Microbiome Facility of the Medical University of Vienna and the University of Vienna, Vienna, Austria

5. Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria

Abstract

Our knowledge concerning the initial gut microbiome assembly in human neonates is limited, and scientific progression in this interdisciplinary field is hindered due to the individuality in composition of gut microbiota. Our study addresses the ecological processes that result in the observed individuality of microbes in the gastrointestinal tract between extremely premature and term-born infants.

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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