Serum Antibody Response to Clostridium botulinum Toxin in Infant Botulism-Reference-Cited by-同舟云学术

Serum Antibody Response to Clostridium botulinum Toxin in Infant Botulism

Published:1982-10 Issue:4 Volume:16 Page:770-771
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Rubin Lorry G.¹,Dezfulian Manuchehr²,Yolken Robert H.¹

Affiliation:

1. Eudowood Division of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

2. Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

Abstract

A serum antibody response has not been previously demonstrated after infection with Clostridium botulinum. We developed an enzyme immunoassay for measuring serum antibody to C. botulinum toxins A, B, and E. This assay system detected a specific immunoglobulin G and immunoglobulin M antibody response to C. botulinum toxin in two patients with infant botulism.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.16.4.770-771.1982

Reference6 articles.

1. Infant botulism: epidemiological, clinical, and laboratory aspects;Arnon S. S.;J. Am. Med. Assoc.,1977

2. Botulism-United States, 1979-1980;Centers for Disease Control.;Morbid. Mortal. Week. Rep.,1981

3. Laboratory procedures for cases of suspected infant botulism;Hatheway C. L.;Rev. Infect. Dis.,1979

4. Quantitation of Clostridium botulinum organisms and toxin in the feces of an infant with botulism;Paton J. C.;J. Clin. Microbiol.,1982

5. Syndrome of botulism in infancy: clinical and electrophysiologic study;Pickett J.;N. EngI. J. Med.,1976

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