Circulating 20S Proteasome Levels in Patients with Mixed Connective Tissue Disease and Systemic Lupus Erythematosus-Reference-Cited by-同舟云学术

Circulating 20S Proteasome Levels in Patients with Mixed Connective Tissue Disease and Systemic Lupus Erythematosus

Published:2008-09 Issue:9 Volume:15 Page:1489-1493
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Majetschak Matthias¹²³,Perez Magdalena¹²³,Sorell Luis T.¹²³,Lam Janet¹²³,Maldonado Marcos E.¹²³,Hoffman Robert W.¹²³

Affiliation:

1. The Burn and Shock Trauma Institute and Department of Surgery, Loyola University Chicago Stritch School of Medicine, Chicago, Illinois

2. Division of Trauma and Surgical Critical Care—Trauma Research, DeWitt Daughtry Family Department of Surgery

3. Division of Rheumatology and Immunology, Department of Medicine, University of Miami Miller School of Medicine, and the Miami Veteran Affairs Medical Center, Miami, Florida

Abstract

ABSTRACT The associations of circulating 20S proteasomes (c20S) with clinical and serologic disease indices in patients with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) are unknown. We present the initial report that c20S levels are elevated in MCTD and correlate with clinically relevant changes in disease activity in SLE and MCTD.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00187-08

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