Identification of a Proline-Kinked Amphipathic α-Helix Downstream from the Methyltransferase Domain of a Potexvirus Replicase and Its Role in Virus Replication and Perinuclear Complex Formation-Reference-Cited by-同舟云学术

Identification of a Proline-Kinked Amphipathic α-Helix Downstream from the Methyltransferase Domain of a Potexvirus Replicase and Its Role in Virus Replication and Perinuclear Complex Formation

Published:2021-09-27 Issue:20 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Komatsu Ken¹²^ORCID,Sasaki Nobumitsu²³,Yoshida Tetsuya⁴,Suzuki Katsuhiro¹,Masujima Yuki¹,Hashimoto Masayoshi⁴,Watanabe Satoru⁵,Tochio Naoya⁵,Kigawa Takanori⁵,Yamaji Yasuyuki⁴,Oshima Kenro⁶,Namba Shigetou⁴,Nelson Richard S.⁷,Arie Tsutomu¹²^ORCID

Affiliation:

1. Laboratory of Plant Pathology, Graduate School of Agriculture, Tokyo University of Agriculture and Technology (TUAT), Fuchu, Japan

2. Institute of Global Innovation Research (GIR), Tokyo University of Agriculture and Technology (TUAT), Fuchu, Japan

3. Gene Research Center, Tokyo University of Agriculture and Technology (TUAT), Fuchu, Japan

4. Laboratory of Plant Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

5. Laboratory for Cellular Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan

6. Faculty of Bioscience, Department of Clinical Plant Science, Hosei University, Koganei, Japan

7. Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, Oklahoma, USA

Abstract

RNA viruses characteristically associate with intracellular membranes during replication. Although virus replicases are assumed to possess membrane-targeting properties, their membrane association domains generally remain unidentified or poorly characterized.

Funder

the Program for Promotion of Basic Research Activities for Innovative Bioscience

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01906-20

Reference84 articles.

1. Viral Manipulation of Plant Host Membranes

2. Host factors used by positive-strand RNA plant viruses for genome replication