Affiliation:
1. Center for Microbial Ecology, Michigan State University, East Lansing 48824.
Abstract
Excision of phage Mu from Escherichia coli MCS2 was originally put forth as a clear example of directed mutation. This claim was considerably weakened, however, by subsequent evidence that Mu excision occurs during starvation regardless of fitness consequences. Here, I use the classical replica-plating technique to examine Mu excision during starvation of MCS2. The results support the conclusion that Mu excision is not directed but is, instead, nonspecifically induced by starvation.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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