Affiliation:
1. JMI Laboratories, North Liberty, Iowa, USA
Abstract
ABSTRACT
Fusidic acid (FA) activity was evaluated against 2,002 clinical staphylococcal isolates collected in U.S. hospitals during 2014. FA (MIC
50/90
, 0.12/0.12 μg/ml) inhibited 99.8% of
Staphylococcus aureus
isolates at ≤1 μg/ml. Only four
S. aureus
isolates displayed FA values of >2 μg/ml (three strains with
fusC
and one with an L461K substitution in
fusA
), and they were isolated from patients in four states. In conclusion, FA demonstrated sustained, potent activity against this recent collection of U.S. staphylococci.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
25 articles.
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