Amphotericin B- and Fluconazole-Resistant Candida spp., Aspergillus fumigatus , and Other Newly Emerging Pathogenic Fungi Are Susceptible to Basic Antifungal Peptides-Reference-Cited by-同舟云学术

Amphotericin B- and Fluconazole-Resistant Candida spp., Aspergillus fumigatus , and Other Newly Emerging Pathogenic Fungi Are Susceptible to Basic Antifungal Peptides

Published:1999-03 Issue:3 Volume:43 Page:702-704
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Helmerhorst Eva J.¹,Reijnders Ingrid M.¹,van ’t Hof Wim¹,Simoons-Smit Ina²,Veerman Enno C. I.¹,Amerongen Arie V. Nieuw¹

Affiliation:

1. Academic Centre for Dentistry (ACTA), Department of Oral Biochemistry, Vrije Universiteit,1 and

2. Department of Clinical Microbiology, Academic Hospital Vrije Universiteit (AZVU),2 Amsterdam, The Netherlands

Abstract

ABSTRACT The present study shows that a number of basic antifungal peptides, including human salivary histatin 5, a designed histatin analog designated dhvar4, and a peptide from frog skin, PGLa, are active against amphotericin B-resistant Candida albicans , Candida krusei , and Aspergillus fumigatus strains and against a fluconazole-resistant Candida glabrata isolate.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.43.3.702

Reference21 articles.

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5. Synthetic histatin analogs with broad-spectrum antimicrobial activity.;Helmerhorst E. J.;Biochem. J.,1997

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