Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance-Reference-Cited by-同舟云学术

Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance

Published:2021-12-22 Issue:6 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Yoshino Mai¹,Aihara Masamune¹^ORCID,Gotoh Yasuhiro²,Akimoto Masaru¹,Tatsuhara Wakana³,Kiyosuke Makiko¹,Matsushima Yuichi⁴,Uchiumi Takeshi³,Hayashi Tetsuya²^ORCID,Kang Dongchon¹⁴

Affiliation:

1. Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Hospital, Fukuoka, Japan

2. Department of Bacteriology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

3. Department of Health Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

4. Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Abstract

Within-host evolution is a survival strategy that can occur in many pathogens and is often associated with the emergence of novel antimicrobial-resistant (AMR) bacteria. To analyze this process, suitable sets of clinical isolates are required.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00734-21

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