Disruption of Toxoplasma gondii-Induced Host Cell DNA Replication Is Dependent on Contact Inhibition and Host Cell Type-Reference-Cited by-同舟云学术

Disruption of Toxoplasma gondii-Induced Host Cell DNA Replication Is Dependent on Contact Inhibition and Host Cell Type

Published:2022-06-29 Issue:3 Volume:7 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Pierre-Louis Edwin¹,Etheridge Menna G.¹,de Paula Baptista Rodrigo²,Khan Asis³,Chasen Nathan M.¹,Etheridge Ronald D.¹^ORCID

Affiliation:

1. Department of Cellular Biology, Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, Georgia, USA

2. Infectious Diseases & Pathology Research Team, Houston Methodist Research Institute, Houston, Texas, USA

3. Molecular Parasitology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, USA

Abstract

Toxoplasma gondii chronically infects approximately one-third of the global population and can produce severe pathology in immunologically immature or compromised individuals. During infection, this parasite releases numerous host-targeted effector proteins that can dramatically alter the expression of a variety of host genes.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00160-22

Reference83 articles.

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3. Host Cell Invasion by Malaria Parasites