Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans-Reference-Cited by-同舟云学术

Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans

Published:2021-05-19 Issue: Volume: Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Mosterd Cas¹²,Moineau Sylvain¹²³^ORCID

Affiliation:

1. Département de Biochimie, de Microbiologie, et de Bio-informatique, Faculté des Sciences et de Génie, Université Laval, Québec City, Québec, Canada

2. Groupe de Recherche en Écologie Buccale, Faculté de Médecine Dentaire, Université Laval, Québec City, Québec, Canada

3. Félix d’Hérelle Reference Center for Bacterial Viruses, Université Laval, Québec City, Québec, Canada

Abstract

Bacteria are under the constant threat of viral predation and have therefore developed several defense mechanisms, including CRISPR-Cas systems. While studies on the mode of action of CRISPR-Cas systems have already provided great insights into phage-bacterium interactions, still more information is needed on the biology of these systems.

Funder

Canada Research Chairs

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00185-21

Reference48 articles.

1. A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus

2. Systematic discovery of antiphage defense systems in the microbial pangenome