Affiliation:
1. School of Life Sciences, Central China Normal University, Wuhan, China
Abstract
The dependence of cell size on growth rate is a fundamental principle in the field of bacterial cell size regulation. Previous studies of cell size regulation mainly focus on fast-growing bacterial species such as
Escherichia coli
and
Bacillus
subtilis
. We find here that
Sinorhizobium meliloti
, a slow-growing bacterium, exhibits a remarkable growth rate-dependent cell size pattern under nutrient limitation, generalizing the applicability of the empirical nutrient growth law of cell size. Moreover,
S. meliloti
exhibits a much slower speed of cell cycle progression than
E. coli
does, suggesting a delicate coordination between the cell cycle progression rate and the biomass growth rate.
Funder
National Natural Science Foundation of China
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
11 articles.
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