Immunogenicity and Efficacy of Live-Attenuated Salmonella Typhimurium Vaccine Candidate CVD 1926 in a Rhesus Macaque Model of Gastroenteritis-Reference-Cited by-同舟云学术

Immunogenicity and Efficacy of Live-Attenuated Salmonella Typhimurium Vaccine Candidate CVD 1926 in a Rhesus Macaque Model of Gastroenteritis

Published:2021-09-16 Issue:10 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Higginson Ellen E.¹²,Panda Aruna³⁴⁵,Toapanta Franklin R.¹²,Terzi Matthew C.³⁴,Jones Jennifer A.¹²,Sen Sunil¹²,Permala-Booth Jasnehta¹²,Pasetti Marcela F.¹²⁶,Sztein Marcelo B.¹²⁶,DeTolla Louis²³⁴⁵,Levine Myron M.¹²⁶,Tennant Sharon M.¹²^ORCID

Affiliation:

1. Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

2. Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA

3. Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA

4. Program of Comparative Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA

5. Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

6. Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA

Abstract

Salmonella Typhimurium is a common cause of foodborne gastroenteritis and a less frequent but important cause of invasive disease, especially in developing countries. In our previous work, we showed that a live-attenuated S. Typhimurium

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00087-21

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