Applications of Bacillus subtilis Spores in Biotechnology and Advanced Materials

Author:

Zhang Xiaopei1,Al-Dossary Amal2,Hussain Myer1,Setlow Peter3,Li Jiahe1ORCID

Affiliation:

1. Department of Bioengineering, Northeastern University, Boston, Massachusetts, USA

2. Department of Biology, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

3. Department of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut, USA

Abstract

The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of B. subtilis , its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications.

Funder

DOD | United States Army | MEDCOM | Congressionally Directed Medical Research Programs

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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