Affiliation:
1. Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India
Abstract
The rising incidence of non-albicans
Candida
species globally, along with the emergence of drug resistance, is a cause for concern. This study investigated the protective efficacy of secreted aspartyl proteinase 2 (Sap2) in systemic
C. tropicalis
infection. Vaccination with recombinant Sap2 (rSap2) protein from
C. parapsilosis
enhanced survival of mice compared to rSap2 vaccinations from
C. albicans
(
P
= 0.
Funder
DST | Science and Engineering Research Board
Ministry of Human Resource Development
Department of Biotechnology, Ministry of Science and Technology, India
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
25 articles.
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