Whole-Genome-Based Public Health Surveillance of Less Common Shiga Toxin-Producing Escherichia coli Serovars and Untypeable Strains Identifies Four Novel O Genotypes

Author:

Lang Christina1,Hiller Miriam1,Konrad Regina2,Fruth Angelika1,Flieger Antje1

Affiliation:

1. Division of Enteropathogenic Bacteria and Legionella, National Reference Centre for Salmonella and Other Enteric Bacterial Pathogens, Robert Koch Institute, Wernigerode, Germany

2. Department of Infectiology, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany

Abstract

Shiga toxin-producing Escherichia coli (STEC) and the STEC subgroup enterohemorrhagic E. coli cause intestinal infections with symptoms ranging from watery diarrhea to hemolytic-uremic syndrome (HUS). A key tool for the epidemiological differentiation of STEC is serotyping. The serotype in combination with the main virulence determinants gives important insight into the virulence potential of a strain.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference46 articles.

1. Public Health Microbiology of Shiga Toxin-Producing Escherichia coli

2. Frankreich Jahrbuch 2016

3. European Centre for Disease Prevention and Control. 2015. Surveillance of seven priority food- and waterborne diseases in the EU/EEA 2010-2012. European Centre for Disease Prevention and Control, Stockholm, Sweden.

4. Pathogenic Escherichia coli

5. Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

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