Antimicrobial Resistance in Shigella flexneri and Shigella sonnei in Hong Kong, 1986 to 1995

Author:

Chu Yiu-wai1,Houang Elizabeth T. S.1,Lyon Donald J.1,Ling Julia M.1,Ng Tak-keung2,Cheng Augustine F. B.1

Affiliation:

1. Department of Microbiology, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, New Territories,1 and

2. Department of Pathology, Princess Margaret Hospital, Kowloon,2Hong Kong

Abstract

ABSTRACT Three hundred and thirty-three Shigella isolates obtained in 1986 to 1995 were tested for their susceptibilities to 19 antimicrobial agents. Nalidixic acid resistance had emerged in 59.6% of Shigella flexneri isolates during 1994 to 1995, with all tested resistant isolates having the mutation in gyrA encoding the Ser-83 alteration. Multiresistance (resistance to four or more agents) was more common in S. flexneri than in Shigella sonnei.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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