Affiliation:
1. Biosynexus, Inc., Gaithersburg, Maryland 20877
Abstract
ABSTRACT
Lysostaphin is an endopeptidase that kills
Staphylococcus aureus
, a predominant organism in catheter-related infections. Lysostaphin-coated catheters prevented catheter colonization by several strains of
S. aureus
, and activity was maintained for at least 4 days. Prophylactic use of lysostaphin in catheters may help prevent the occurrence of catheter-related staphylococcal infections.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
69 articles.
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