Recombinant Cysteine Proteinase B from Leishmania braziliensis and Its Domains: Promising Antigens for Serodiagnosis of Cutaneous and Visceral Leishmaniasis in Dogs-Reference-Cited by-同舟云学术

Recombinant Cysteine Proteinase B from Leishmania braziliensis and Its Domains: Promising Antigens for Serodiagnosis of Cutaneous and Visceral Leishmaniasis in Dogs

Published:2019-11 Issue:11 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Bivona A. E.¹²,Czentner L.¹²,Sanchez Alberti A.¹²,Cerny N.²,Cardoso Landaburu A. C.¹²,Nevot C.³,Estévez O.³,Marco J. D.⁴,Basombrio M. A.⁴,Malchiodi E. L.¹²,Cazorla S. I.²⁵

Affiliation:

1. Cátedra de Inmunología and Instituto de Estudios de la Inmunidad Humoral (IDEHU), CONICET-UBA, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina

2. Instituto de Microbiología y Parasitología Médica, IMPaM (UBA-CONICET), Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, UBA, Buenos Aires, Argentina

3. Veterinaria del Oeste, Posadas, Argentina

4. Instituto de Patología Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Salta, Salta, Argentina

5. Laboratorio de Inmunología, Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina

Abstract

Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions. Leishmaniasis is one of the major tropical neglected diseases, with 1.5 to 2 million new cases occurring annually. Diagnosis remains a challenge despite advances in parasitological, serological, and molecular methods. Dogs are an important host for the parasite and develop both visceral and cutaneous lesions.

Funder

University of Buenos Aires

Agencia Nacional de Promoción Científica y Técnica, Argentina

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00819-19

Reference52 articles.

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