The Fiber Knob Protein of Human Adenovirus Type 49 Mediates Highly Efficient and Promiscuous Infection of Cancer Cell Lines Using a Novel Cell Entry Mechanism-Reference-Cited by-同舟云学术

The Fiber Knob Protein of Human Adenovirus Type 49 Mediates Highly Efficient and Promiscuous Infection of Cancer Cell Lines Using a Novel Cell Entry Mechanism

Published:2021-01-28 Issue:4 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Baker Alexander T.¹^ORCID,Davies James A.¹,Bates Emily A.¹,Moses Elise¹,Mundy Rosie M.¹,Marlow Gareth¹,Cole David K.²,Bliss Carly M.¹²,Rizkallah Pierre J.²,Parker Alan L.¹^ORCID

Affiliation:

1. Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom

2. Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom

Abstract

Adenoviruses are powerful tools experimentally and clinically. To maximize efficacy, the development of serotypes with low preexisting levels of immunity in the population is desirable.

Funder

Cancer Research UK

Wellcome

Tenovus

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01849-20

Reference49 articles.

1. Designer Oncolytic Adenovirus: Coming of Age