Isolation of the Fungus Geosmithia argillacea in Sputum of People with Cystic Fibrosis

Author:

Barton R. C.1,Borman A. M.2,Johnson E. M.2,Houbraken J.3,Hobson R. P.1,Denton M.4,Conway S. P.5,Brownlee K. G.5,Peckham D.5,Lee T. W. R.5

Affiliation:

1. Mycology Reference Centre

2. HPA Mycology Reference Laboratory, HPA Southwest, Bristol, United Kingdom

3. CBS—Fungal Biodiversity Centre, Uppsalalaan 8, 3584 CT Utrecht, Netherlands

4. Department of Microbiology, Leeds General Infirmary, Leeds LS1 3EX, United Kingdom

5. Leeds Regional Cystic Fibrosis Centre, St. James's University Hospital, Leeds LS9 7TF, United Kingdom

Abstract

ABSTRACT We report the repeated isolation of the fungus Geosmithia argillacea from sputum samples of people with cystic fibrosis. Identification was based on morphology and DNA sequence analysis. Isolation of G. argillacea did not appear to be associated with clinical deterioration. The pathogenic potential of G. argillacea is discussed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference10 articles.

1. Borman, A. M., C. K. Campbell, C. J. Linton, P. D. Bridge, and E. M. Johnson. 2006. Polycytella hominis is a mutated form of Scedosporium apiospermum. Med. Mycol. 44 : 33-39.

2. Borman, A. M., C. J. Linton, S.-J. Miles, C. K. Campbell, and E. M. Johnson. 2006. Ultra-rapid preparation of total genomic DNA from isolates of yeast and mould using Whatman FTA filter paper technology—a re-usable DNA archiving system. Med. Mycol. 44 : 389-398.

3. Cimon, B., J. Carrere, J. P. Chazalette, J. F. Vinatier, D. Chabasse, and J. P. Bouchara. 1999. Chronic airway colonization by Penicillium emersonii in a patient with cystic fibrosis. Med. Mycol. 37 : 291-293.

4. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi; approved standard M38-A. 2002

5. Cystic Fibrosis. 2009

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