Viral Manipulation of a Mechanoresponsive Signaling Axis Disassembles Processing Bodies-Reference-Cited by-同舟云学术

Viral Manipulation of a Mechanoresponsive Signaling Axis Disassembles Processing Bodies

Published:2021-10-26 Issue:11 Volume:41 Page:
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Castle Elizabeth L.¹,Robinson Carolyn-Ann²³,Douglas Pauline⁴²,Rinker Kristina D.⁴⁵²,Corcoran Jennifer A.¹²³^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada

2. Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada

3. Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

4. Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada

5. Department of Chemical and Petroleum Engineering and Centre for Bioengineering Research and Education, University of Calgary, Calgary, Alberta, Canada

Abstract

Processing bodies (PBs) are ribonucleoprotein granules important for cytokine mRNA decay that are targeted for disassembly by many viruses. Kaposi’s sarcoma-associated herpesvirus is the etiological agent of the inflammatory endothelial cancer, Kaposi’s sarcoma, and a PB-regulating virus.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MCB.00399-21

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