Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages-Reference-Cited by-同舟云学术

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages

Published:2021-08-31 Issue:4 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Bell Samantha L.¹^ORCID,Lopez Kayla L.¹,Cox Jeffery S.²,Patrick Kristin L.¹,Watson Robert O.¹^ORCID

Affiliation:

1. Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, Texas, USA

2. Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA

Abstract

Mycobacterium tuberculosis (Mtb) infects one-quarter of the global population and causes one of the deadliest infectious diseases worldwide. Macrophages are the first line of defense against Mtb infection and are typically incredibly efficient at destroying intracellular pathogens, but Mtb has evolved to survive and replicate in this harsh environment.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01871-20

Reference74 articles.

1. World Health Organization. 2019. Global tuberculosis report 2019. World Health Organization, Geneva, Switzerland.

2. Macrophage defense mechanisms against intracellular bacteria