In Vitro Synergy of Daptomycin plus Rifampin against Enterococcus faecium Resistant to both Linezolid andVancomycin-Reference-Cited by-同舟云学术

In Vitro Synergy of Daptomycin plus Rifampin against Enterococcus faecium Resistant to both Linezolid andVancomycin

Published:2005-12 Issue:12 Volume:49 Page:5166-5168
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Pankey George¹,Ashcraft Deborah¹,Patel Nalini¹

Affiliation:

1. Ochsner Clinic Foundation, New Orleans, Louisiana

Abstract

ABSTRACT In vitro synergy testing of daptomycin plus rifampin was performed against 24 unique isolates of Enterococcus faecium resistant to both linezolid and vancomycin. Synergy testing showed that 21/24 (88%) were synergistic and 3/24 (12%) were indifferent by the Etest method. Time-kill assays revealed synergy for 18/24 (75%) and indifference for 6/24 (25%).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.12.5166-5168.2005

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