Cg Hog1-Mediated Cg Rds2 Phosphorylation Alters Glycerophospholipid Composition To Coordinate Osmotic Stress in Candida glabrata-Reference-Cited by-同舟云学术

Cg Hog1-Mediated Cg Rds2 Phosphorylation Alters Glycerophospholipid Composition To Coordinate Osmotic Stress in Candida glabrata

Published:2019-03-15 Issue:6 Volume:85 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Wu Chengjin¹²³,Zhang Jiali¹³,Zhu Guoxing¹²³,Yao Rui¹²³,Chen Xiulai¹²³,Liu Liming¹²³

Affiliation:

1. State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China

2. The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, Jiangsu, China

3. Laboratory of Food Microbial-Manufacturing Engineering, Jiangnan University, Wuxi, Jiangsu, China

Abstract

This study explored the role of Cg Hog1-mediated Cg Rds2 phosphorylation in response to osmotic stress in Candida glabrata . Cg Hog1 interacts with and phosphorylates Cg Rds2, a zinc cluster transcription factor, under osmotic stress. Phosphorylated Cg Rds2 plays an important role in increasing glycerophospholipid composition and membrane integrity, thereby enhancing cell growth and survival.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02822-18

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