Differential Infectivity and Division of Toxoplasma gondii in Human Peripheral Blood Leukocytes

Author:

Channon Jacqueline Y.1,Seguin Rosanne M.2,Kasper Lloyd H.2

Affiliation:

1. Departments of Microbiology1 and

2. Medicine,2 Dartmouth Medical School, Lebanon, New Hampshire 03756

Abstract

ABSTRACT When tachyzoites were incubated with human peripheral blood leukocytes in vitro, more monocytes and dendritic cells than neutrophils or lymphocytes were infected. Although tachyzoites were able to divide in each of these cell types, monocytes and dendritic cells were more permissive to rapid tachyzoite division than neutrophils or lymphocytes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference33 articles.

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4. Human microglial cell defense against Toxoplasma gondii. The role of cytokines;Chao C. C.;J. Immunol.,1994

5. Effect of IFN-gamma on the proliferation of Toxoplasma gondii in monocytes and monocyte-derived macrophages from AIDS patients;Delemarre F. G.;Immunology,1994

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