Glucagon-like Peptide-1 Receptor Agonists for Weight Loss in Orthopaedic Surgery: A Comprehensive Review

Author:

Spence Dominique B.1ORCID,Austin Roman1,Carrol Colin1,Pierce Suki1,Richter Dustin L.1,Chamberlain Rachel1,Schenck Robert C.1

Affiliation:

1. University of New Mexico, School of Medicine, Albuquerque, New Mexico

Abstract

Obesity is a well-documented risk factor of complications and poor patient outcomes after orthopaedic surgery. Glucagon-like peptide-1 (GLP-1) receptor agonists can be an effective way to achieve patients’ weight loss goals that are more facile than previously used weight loss avenues. Other weight loss medications and bariatric surgery have significant side effects and complications. GLP-1 has decreased cardiac morbidity and mortality, profoundly affects weight loss, and allows for better glucose control in patients with diabetes. GLP-1 should be temporarily discontinued one dose before general anesthesia due to slowed gastric emptying.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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