Impact of taxane-based chemotherapeutics on male reproductive function-Reference-Cited by-同舟云学术

Impact of taxane-based chemotherapeutics on male reproductive function

Published:2023-01-01 Issue:1 Volume:4 Page:
ISSN:2633-8386
Container-title:Reproduction and Fertility
language:
Short-container-title:

Author:

Kanodia Charvi¹^ORCID,Rimmer Michael P²^ORCID,Duffin Kathleen³^ORCID,Mitchell Rod T²^ORCID

Affiliation:

1. Edinburgh Medical School, University of Edinburgh, UK

2. MRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UK

3. Biomedical Sciences, University of Edinburgh, UK

Abstract

Lay summary Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemotherapy drugs, called taxanes, on testicular function and fertility. More studies are needed to aid clinicians in advising patients on how this taxane-based chemotherapy may affect their future fertility.

Publisher

Bioscientifica

Subject

Urology,Reproductive Medicine,Obstetrics and Gynecology,Embryology

Link

https://raf.bioscientifica.com/downloadpdf/journals/raf/4/1/RAF-22-0134.xml

Reference7 articles.

1. Low testosterone levels and increased inflammatory markers in patients with cancer and relationship with cachexia;Burney,2012

2. Effects of taxane-based chemotherapy on inhibin B and gonadotropins as biomarkers of spermatogenesis;Chatzidarellis,2010

3. Autologous grafting of cryopreserved prepubertal rhesus testis produces sperm and offspring;Fayomi,2019

4. Testicular function in poor-risk nonseminomatous germ cell tumors treated with methotrexate, paclitaxel, ifosfamide, and cisplatin combination chemotherapy;Pectasides,2009

5. Baseline characteristics and patterns of care in testicular cancer patients: first data from the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS);Rothermundt,2018