THE SHORT-TERM MAINTENANCE OF THE ISOLATED SHEEP FOETUS IN THE LAST FIFTH OF PREGNANCY.

Abstract

ABSTRACT A method is described for the maintenance of the isolated sheep foetus in the last fifth of gestation. The advantages of this particular technique are described in comparison with others previously reported. The simplicity of the technique without the need for exogenous blood or anticoagulants and the well-maintained physiological condition of the foetus throughout are the essential benefits of the method. The preparation has been used in the study of the metabolism of tritiated pregnenolone and carbon-labelled progesterone. Preliminary results on the isolation of circulating metabolites are described.