Ethanol Extraction of Hoya Carnosa Leaves Improved Stroma of Middle Ear Epithelium Infected by Pseudomonas Aeruginosa-Reference-Cited by-同舟云学术

Ethanol Extraction of Hoya Carnosa Leaves Improved Stroma of Middle Ear Epithelium Infected by Pseudomonas Aeruginosa

Published:2019-03-23 Issue:1 Volume:12 Page:171-173
ISSN:0974-6242
Container-title:Biomedical and Pharmacology Journal
language:
Short-container-title:Biomed. Pharmacol. J.

Author:

Lely Rahayu Made¹,Bakta I. Made²,Suardana Wayan¹,Mantik Astawa Nyoman³,Arijana I. G. K.⁴,Tunas I. Ketut⁵

Affiliation:

1. Department of Otorhinolaryngology-Head and Neck surgery Faculty of Medicine Udayana University/Sanglah General Hospital Denpasar, Bali, Indonesia.

2. Departement of Internal Medicine Faculty of Medicine Udayana University/Sanglah General Hospital Denpasar, Bali, Indonesia.

3. Pathobiology Laboratory of Faculty of Veterinary Medicine Udayana University, Bali, Indonesia.

4. Department of Histology Faculty of Medicine Udayana University, Bali, Indonesia.

5. Department of Public Health, Faculty of Health, Science and Technology, Dhyana Pura University, Bali, Indonesia.

Abstract

Hoya carnosa leaves or tebel-tebel leaves are known by the Balinese people in the countryside to treat middle ear infections in the medical language, otitis media or “curek” in the Balinese language. The study is true experimental randomized posttest-only control group design to evaluate the impact of ethanol extract sample as antibacterial. As antibacterial, the extract has an impact on the thickness of stroma middle ear epithelium with otitis media due to Pseudomonas Aeruginosa. The result showed average mean thickness stroma in the treatment group lower than controls.

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology

Reference8 articles.

1. Lee S. K., Park D. C., Kim M. G., Boo S. H., Choi Y. J., Byun J. Y., Park M. S & Yeo S. G. Rate of isolation and trends of antimicrobial resistance of multidrug resistant pseudomonas aeruginosa from otorrhea in chronic suppurative otitis media. Clin exp otorhinolaryngol. 2012;5:17-22.

2. CrossRef

3. Vlastarakos V. V., Nikolopoulos T. P., Maragoudakis P., Tzagaroulakis A & Ferekidis E. Biofilms in ear, nose and throat infections: how important are they? The laryngoscope. 2007;117:668-73.

4. CrossRef

5. Jang C. H., Cho Y. B & Choi C. H. Structural features of tympanostomy biofilm formation tube in ciprofloxacin-resistant pseudomonas otorrhea. International journal of pediatric otorhinolaryngology. 2007;71:591-595.

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