Phytochemical Screening and Mass Spectral Analysis of Azadirachta indica. Linn. Gum-Reference-Cited by-同舟云学术

Phytochemical Screening and Mass Spectral Analysis of Azadirachta indica. Linn. Gum

Published:2022-04-29 Issue:2 Volume:38 Page:452-458
ISSN:2231-5039
Container-title:Oriental Journal Of Chemistry
language:en
Short-container-title:Orient. J. Chem

Author:

J. Mercija J. Mercija¹^ORCID,T. Nevaditha N.¹^ORCID

Affiliation:

1. Department of Chemistry, Nesamony Memorial Christian College, Marthamdam, Affiliated to Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli – 627012.

Abstract

Azadirachta indica is a member of the Meliaceae family, is well-known for its therapeutic properties. Neem gum is a commercially available product that is used in a variety of industries. The crude Neem gum is collected in this study, with water as the purifying solvent and ethyl alcohol as the precipitating agent. Secondary metabolites have been screened in neem gum. FTIR spectroscopy is used to identify the functional biomolecules in the gum. According to mass spectral analysis, fatty acids make up 50% of neem gum. The antibacterial activity of gum against several bacterial pathogens was tested using the disc diffusion method. The gum is more active and reveals that it can be utilised to treat antibiotic-resistant illnesses as an alternative to antibiotics. These findings reveal that the gum in question may be used to create a novel medicinal medication.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

Reference29 articles.

1. 1. Arumugam, P. Agullo, T. Boopalan, S. Nandy, R. Lopez, C. Gutierrez, L. Rajkumar Neem leaf extract inhibits mammary carcinogenesis by altering cell proliferation, apoptosis, and angiogenesis Cancer Biology and Therapy, 15 (1) (2014), pp. 26-34, 10.4161/cbt.26604.

2. 2. A.A. Oyagbemi, O.A. Adejumobi, E.V. Orherhe, A.S. Amid, A.A. Adedapo, …, M.A. YakuuPreconditioning with Azadirachta indica ameliorates cardiorenal dysfunction through reduction in oxidative stress and extracellular signal regulated protein kinase signalling Journal of Ayurveda and Integrative Medicine, 7 (4) (2016), pp. 209 217, 10.1016/j.jaim.2016.08.006.

3. 3. .M. Patel, K.C.N. Venkata, P. Bhattacharyya, G. Sethi, A. Bishayee Potential of neem (Azadirachta indica L.) for prevention and treatment of oncologic diseases Seminars in Cancer Biology, 40–41 (2016), pp. 100-115, 10.1016/j.semcancer.2016.03.002.

4. 4. R. Rupani, A. Chavez Medicinal plants with traditional use: Ethnobotany in the Indian subcontinent Clinics in Dermatology, 36 (3) (2018), pp. 306-309, 10.1016/j.clindermatol.2018.03.005.

5. 5. O. Verma, S. Ponan, A. Kamin Phytochemical screening of Ocimum sanctum (Tulsi), Azadirachta indica (Neem) and Phyllanthus emblica (Amla) International Journal of Current Microbiology and Applied Sciences, 8 (4) (2019), pp. 682-688