Green Synthesis and Antimicrobial Activities of Some Aromatic Hydrazones

Abstract

The condensation reaction of Benzil with semicarbazide followed by a triazine ring formation and then subsequent interaction with substituted aromatic aldehydes, resulted in synthesis of aromatic hydrazone derivatives (C1 – C4). These derivatives have been synthesized via greener method using acetic acid rather than conc. Sulfuric acid. The resultant compounds were analyzed using spectral (1H-NMR, IR) and elemental analysis. The in-vitro analysis of these compounds portrayed prominent activity against bacterial and fungal strains.