Comment on “Opioid antagonists to prevent olanzapine-induced weight gain: A systematic review”

Author:

Todtenkopf Mark S.1ORCID,Correll Christoph U.2ORCID,Harris-White Marni E.3ORCID,Doane Michael J.4ORCID,McDonnell DavidORCID

Affiliation:

1. 1 Director, Scientific Communications, Alkermes Inc, Waltham, Massachusetts

2. 2 Professor of Psychiatry, The Zucker Hillside Hospital, Department of Psychiatry, Northwell Health, Glen Oaks, New York; Professor of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Department of Psychiatry and Molecular Medicine, Hempstead, New York; Professor of Child and Adolescent Psychiatry and Department Chair, Charité Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany

3. 3 Medical Director, Medical Affairs Strategy, Alkermes Inc, Waltham, Massachusetts

4. 4 Director, Health Economics & Outcomes Research, Alkermes Inc, Waltham, Massachusetts

Publisher

College of Psychiatric and Neurologic Pharmacists (CPNP)

Subject

Pharmacology (medical),Neurology (clinical),General Pharmacology, Toxicology and Pharmaceutics,Neuropsychology and Physiological Psychology

Reference11 articles.

1. Opioid antagonists to prevent olanzapine-induced weight gain: a systematic review;Laguado;Ment Health Clin,2022

2. Mitigation of olanzapine-induced weight gain with samidorphan, an opioid antagonist: a randomized double-blind phase 2 study in patients with schizophrenia;Martin;Am J Psychiatry,2019

3. Effects of olanzapine combined with samidorphan on weight gain in schizophrenia: a 24-week phase 3 study;Correll;Am J Psychiatry,2020

4. Olanzapine/samidorphan in young adults with schizophrenia, schizophreniform disorder, or bipolar I disorder who are early in their illness: results of the ENLIGHTEN-Early study (NCT03187769) [oral presentation];Kahn

5. A randomized, double-blind, placebo-controlled proof of concept study to evaluate samidorphan in the prevention of olanzapine-induced weight gain in healthy volunteers;Silverman;Schizophr Res,2018

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