Protein turnover in individual tissues: methods of measurement and relations to RNA.

Abstract

The varying rates of protein turnover in different tissues, viz. serum proteins, intestinal wall, kidneys, spleen, liver, heart, testes, muscles, haemoglobin and skin, are discussed. Also, the use of different methods to measure protein turnover, both protein synthesis and degradation, at these sites, including the use of isotopes and measurements of urinary 3-methyl histidine and measurements done on isolated tissues, suspensions of hepatocytes and cell cultures, is discussed.