Pain Reduction With Oral Methotrexate in Knee Osteoarthritis

Author:

Kingsbury Sarah R.1ORCID,Tharmanathan Puvan2ORCID,Keding Ada2,Watt Fiona E.3ORCID,Scott David L.4,Roddy Edward5ORCID,Birrell Fraser6ORCID,Arden Nigel K.7,Bowes Mike8ORCID,Arundel Catherine2ORCID,Watson Michelle2ORCID,Ronaldson Sarah J.2,Hewitt Catherine2,Doherty Michael9ORCID,Moots Robert J.10ORCID,O’Neill Terence W.11ORCID,Green Michael12,Patel Gulam13,Garrood Toby14,Edwards Christopher J.15,Walmsley Phil J.16,Sheeran Tom17,Torgerson David J.2ORCID,Conaghan Philip G.1ORCID

Affiliation:

1. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health and Care Research (NIHR) Leeds Biomedical Research Centre, Leeds, United Kingdom (S.R.K., P.G.C.)

2. York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, Heslington, York, United Kingdom (P.T., A.K., C.A., M.W., S.J.R., C.H., D.J.T.)

3. Centre for Inflammatory Disease, Department of Immunology and Inflammation, Hammersmith Campus, Imperial College London, and Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, and Department of Rheumatology, Oxford University Hospitals NHS Foundation Trust, and Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, Oxford, United Kingdom (F.E.W.)

4. King's College London, London, United Kingdom (D.L.S.)

5. Primary Care Centre Versus Arthritis, Keele University, and Haywood Academic Rheumatology Centre, Midlands Partnership University NHS Foundation Trust, Keele, United Kingdom (E.R.)

6. Medical Research Council-Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing, Newcastle University, and Northumbria Healthcare NHS Foundation Trust, Newcastle upon Tyne, United Kingdom (F.B.)

7. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, and Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, University of Oxford, Oxford, United Kingdom (N.K.A.)

8. Imorphics, Manchester, United Kingdom (M.B.)

9. Academic Rheumatology and Pain Centre Versus Arthritis, University of Nottingham, Nottingham, United Kingdom (M.D.)

10. Faculty of Heath Social Care and Medicine, Edge Hill University, Ormskirk, and Department of Rheumatology, Aintree University Hospital, Liverpool, United Kingdom (R.J.M.)

11. Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Manchester Academic Health Science Centre, University of Manchester, and NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom (T.W.O.)

12. Harrogate and District NHS Foundation Trust, Harrogate, and York Teaching Hospital NHS Foundation Trust, York, United Kingdom (M.G.)

13. Rheumatology Department, Ashford and St. Peter’s Hospital NHS Trust, Chertsey, United Kingdom (G.P.)

14. Department of Rheumatology, Guy's and St. Thomas' NHS Trust, London, United Kingdom (T.G.)

15. NIHR Southampton Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom (C.J.E.)

16. Department of Orthopaedics, Victoria Hospital Kirkcaldy and School of Medicine, St. Andrews University, Fife and Fife NHS Trust, Kirkcaldy, United Kingdom (P.J.W.)

17. Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, United Kingdom (T.S.).

Publisher

American College of Physicians

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