Affiliation:
1. Meshalkin National Medical Research Center, Ministry of Health of Russian Federation
Abstract
Heart transplantation is the gold standard for the treatment of terminal heart failure. The main method of the donor heart preservation is cold perfusion. The recommended maximum time for cold ischemia of the donor heart is 240 minutes. Exceeding this safe limit increases the risk of postoperative allograft dysfunction and death. However, there are reports positing a possibility to prolong the time of ischemia of the donor heart without a signifi cant risk of complications. The article presents the experience of successful transplantation of the donor heart with the cold ischemia time was 440 minutes.
Publisher
V.I. Shimakov Federal Research Center of Transplantology and Artificial Organs
Subject
Transplantation,Immunology and Allergy
Reference16 articles.
1. Bui AL, Horwich TB, Fonarow GC. Epidemiology and risk profi le of heart failure. Nat. Rev. Cardiol. 2011; 8: 30–41. doi:10.1038/nrcardio.2010.165.
2. Chernyavskiy AM, Efendiev VU, Sirota DA, Alyapkina EM, Efanova OS. Izmenenie kachestva zhizni bol’nyh ishemicheskoi bolezn’ju serdca s vyrazhennoj disfunkciej levogo zheludochka posle hirurgicheskoj revaskuljarizacii miokarda. Patologiya krovoobrashcheniya i kardiokhirurgiya = Circulation Pathology and Cardiac Surgery. 2014; 18 (2): 22–26. doi: http://dx.doi.org/10.21688/1681-3472-2014-2-22-26 [In Russ].
3. Abouna GM. Organ shortage crisis: problems and possible solutions. Transplant Proc. 2008; Jan-Feb; 40 (1): 34–38. doi: 10.1016/j.transproceed.2007.11.067.
4. Erasmus M, Neyrink A, Sabatino M, Potena L. Heart allograft preservation: an arduous journey from the donor to the recipient. Curr Opin Cardiol. 2017; Feb 24. doi: 10.1097/HCO.0000000000000395.
5. Bourge RC, Naftel DC, Costanzo-Nordin MR, Kirklin JK, Young JB, Kubo SH et al. Pretransplantation risk factors for death after heart transplantation: a multiinstitutional study. The Transplant Cardiologists Research Database Group. J. Heart. Lung. Transplant. 1993; JulAug; 12 (4): 549–562.
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