Protein release from poly(ε-caprolactone) microspheres prepared by melt encapsulation and solvent evaporation techniques: A comparative study

Author:

Jameela S.R.1,Suma N.2,Jayakrishnan A.3

Affiliation:

1. a Pnlymer Chemistry Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Science & Technology, Satelmond Palace Campus, Trivandrum 695012, India

2. b Pnlymer Chemistry Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Science & Technology, Satelmond Palace Campus, Trivandrum 695012, India

3. c Pnlymer Chemistry Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Science & Technology, Satelmond Palace Campus, Trivandrum 695012, India

Publisher

Informa UK Limited

Subject

Biomedical Engineering,Biomaterials,Bioengineering,Biophysics

Reference20 articles.

1. Lewis, D. H. 1990. Biodegradable Polymers as Drug Delivery Systems, Drugs and Pharmaceutical Sciences, Edited by: Chasin, M. and Langer, R. Vol. 45, 1New York: Marcel Dekker.

2. Pitt, C. G. 1990. Biodegradable Polymers as Drug Delivery Systems, Drugs and Pharmaceutical Sciences, Edited by: Chasin, M. and Langer, R. Vol. 45, 71New York: Marcel Dekker.

3. A new method for the preparation of drug containing polylactic acid microparticles without using organic solvents

4. Importance of in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulated poly (d,l-lactic acid-co-glycolic acid) microspheres

5. A comparison of alternative methods for the determination of the levels of proteins entrapped in poly(lactide-co-glycolide) microparticles

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