INFLUENCE OF LONG-TERM ADMINISTRATION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON THE LEVEL OF WHOLE GENOME DNA METHYLATION AND ITS FRAGMENTATION IN RATS
Author:
Affiliation:
1. Zaporizhzhia State Medical University
Publisher
Poltava State Medical University
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference11 articles.
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2. Biswas S, Rao CM. Epigenetic tools and their implications in cancer therapy. Eur J Pharmacol. 2018;837:8-24. DOI: 10.1016/j. ejphar.2018.08.021.
3. Han M, Jia L, Lv W, Wang L, Cui W. Epigenetic enzyme mutations: role in tumorigenesis and molecular inhibitors. Front Oncol. 2019;9:194. DOI: 10.3389/fonc.2019.00194.
4. Mohammad HP, Smitheman KN, Kamat CD, Soong D, Federowicz KE, Van Aller GS, et al. A DNA hypomethylation signature predicts antitumor activity of LSD1 inhibitors in SCLC. Cancer Cell. 2015;28:57-69. DOI: 10.1016/j.ccell.2015.06.002.
5. Ferguson-Smith AC. Genomic imprinting: the emergence of an epigenetic paradigm. Nature Reviews Genetics. 2011;12:565-75. DOI: 10.1038/nrg3032.
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