Effect of cyclosporin A (CyA) on the immunopathological lesion of the labial minor salivary glands from patients with Sjogren's syndrome.

Author:

Dalavanga Y A,Detrick B,Hooks J J,Drosos A A,Moutsopoulos H M

Publisher

BMJ

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology

Reference11 articles.

1. syndrome (sicca syndrome): current issues;M, Moutsopoulos H.;Ann Intern Med; 92: 216-26. with Sjogren's syndrome treated with CyA. Furthermore, the ratio of T helper/T suppressor lymphocytes was decreased. To our knowledge there has been no previous study showing that CyA treatment,1980

2. Use of monoclonal antibodies to analyse peripheral blood and salivary gland lymphocyte subsets in Sjogren's syndrome;I, Fox R.; A, Carstens S.; S, Fong; A, Robinson C.; F, Howell; H, Vaughan J.;Arthritis Rheum,1982

3. of an autoimmune disease acts on the immune effector cell population in the affected organ. There are, however, similar findings in the peripheral blood of patients with autoimmune uveitis and Skopouli F N, Detrick B. HLA-DR expression by labial salivary gland tissues in Sj6gren's syndrome;M, Moutsopoulos H.; J, Hooks J.; C, Chan C.; A, Dalavanga Y.;Ann Rheum Dis,1986

4. Minor salivary gland involvement in Sjogren's syndrome;M, Tarpley T.; L, Anderson G.; L, White C.;Oral Surg,1974

5. Cyclosporin A - usefulness, risks and patients, most of our CyA treated patients showed elimination of HLA-DR antigen expression on the glandular epithelial cells. This finding can be attributed to the decreased production of lymphokines mechanisms of action;Britton, S.; Palacios, R.;Immunol Rev,1982

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