1. type I collagen that is laid down in the ex-II (table). They alter sequences that are imtracellular matrix of the dermis, bone, dentine, portant in chain association, disulphide linking sclera, ligaments, and fascia, the tissues affected of the chains, and interactions with in OI
2. Genetic heterogeneity Med Genet;D.M.,1979
3. Substitution of an aspartic acid for glycine 700 in the a2(I) chain of type I collagen in a recurrent lethal type II osteogenesis imperfecta dramatically affects the mineralization of bone;Cohen-Solal, L.; Zylberberg, L.; Sangalli, A.; Gomez Lira, M.; Mottes, M.;_7 Biol Chem,1994
4. Perinatal lethal osteogenesis imperfecta (OI type II): a biochemically heterogeneous disorder usually due to new mutations in the genes for type I collagen;Byers, P.H.; Tsipouras, P.; Bonadio, J.F.; Starman, B.J.; Schwartz, R.C.;Am _7 Hum Genet,1988
5. An intron mutation in the human oal (I) collagen gene alters the efficiency of premRNA splicing and is associated with osteogenesis imperfecta type II. Cohn DH, Zhang. XTB, ioBlyCerhsemPH1.99H0o; m26o5l:o2g2y6-2m-e8d.iated recombination between type I collagen gene exons results in an internal tandem duplication and lethal osteogenesis imperfecta;Bonadio, J.; Ramirez, F.; Barr, M.,1993